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Showing posts with the label Dystrophy

Dystrophy - Pathology of Stromal Vascular Dystrophy

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Pathology of Stromal-Vascular Dystrophy  (mesenchymal, extracellular degenerations) develops as a result of metabolism disorder in the connective tissue and is identified in the stroma of organs and the vascular wall. Development of  Stromal   Vascular   Dystrophy  occurs in the gistion. Gistion is complex, which includes the microvasculature with the surrounding elements of connective tissue: ground substance, fibrous structures, and connective tissue cells. In the case of metabolism disorder, there is an accumulation of metabolism products, which are brought with the blood and lymph, or may be accumulated due to perverted synthesis, in the intercellular substance. Morphogenetic mechanisms of  Stromal Vascular Dystrophy  are such mechanisms as infiltration and perverted synthesis of substances. Causes of  Stromal Vascular Dystrophy  according to  pathology , are infectious and allergic diseases, rheumatic diseases, diseases of blood cir...

Dystrophy - Pathology of Parenchymal, Hyaline-drop & Hydropic Dystrophy

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Parenchymatous dystrophies or Parenchymal Dystrophy (cell degenerations) is based on metabolism disorder and structural changes that occur in specialized cells of parenchymatous organs (liver, myocardium, kidneys). Besides, there is a metabolism disorder of membranous and cytoplasmic proteins, which leads to a change in  their physical and chemical characteristics. The trigger mechanism is the en zyme deficiency - enzymopathies. Table Of Contents Parenchymatous protein dystrophy (proteinosis) -  Parenchymatous protein dystrophy is morphologically characterized by  the appearance of protein granules in the cell cytoplasm. However, the appearance of protein granules may be of a physiological nature, as a manifestation of compensatory and adaptive reaction, without changing its physical and chemical  characteristics and be the result of the physiological activity of cells.  Parenchymatous protein dystrophy includes granular dystrophy, hya line-drop dystrophy, hydro...